KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CACNA1E
All Species:
12.42
Human Site:
S2197
Identified Species:
27.33
UniProt:
Q15878
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15878
NP_000712.2
2313
261731
S2197
E
E
G
S
P
L
T
S
Q
A
L
E
S
N
N
Chimpanzee
Pan troglodytes
XP_520396
2784
310342
I2646
P
L
T
P
R
P
S
I
T
Y
K
T
A
N
S
Rhesus Macaque
Macaca mulatta
XP_001110352
2383
269535
S2194
E
E
G
S
P
L
T
S
Q
A
L
E
N
N
N
Dog
Lupus familis
XP_547425
2465
277756
L2349
L
E
S
T
E
A
G
L
A
E
P
S
G
P
R
Cat
Felis silvestris
Mouse
Mus musculus
Q61290
2272
257217
S2157
E
G
G
S
P
L
A
S
Q
A
L
E
S
N
S
Rat
Rattus norvegicus
Q07652
2222
252098
S2106
E
G
G
S
P
L
A
S
Q
A
L
E
S
N
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O73700
2190
249326
K2079
V
P
N
D
F
R
H
K
H
S
D
K
Q
R
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q2XVR3
1829
207718
R1721
R
Y
A
C
F
M
R
R
S
K
R
K
V
R
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91645
1851
212452
R1743
R
D
L
L
R
D
P
R
D
M
Y
Y
S
S
R
Honey Bee
Apis mellifera
NP_001159376
1904
215872
R1796
V
L
V
T
R
R
G
R
G
R
R
L
P
P
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001186699
1966
222605
R1858
S
R
D
H
S
P
M
R
L
P
P
P
Q
H
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
47.8
95.8
90.7
N.A.
94.6
92.5
N.A.
N.A.
26.4
N.A.
20.4
N.A.
43.5
46.2
N.A.
39.5
Protein Similarity:
100
57.8
96.3
92
N.A.
95.8
93.8
N.A.
N.A.
41.9
N.A.
37.4
N.A.
55.8
57.8
N.A.
52.5
P-Site Identity:
100
6.6
93.3
6.6
N.A.
80
80
N.A.
N.A.
0
N.A.
6.6
N.A.
6.6
0
N.A.
0
P-Site Similarity:
100
26.6
100
13.3
N.A.
86.6
86.6
N.A.
N.A.
20
N.A.
20
N.A.
20
6.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
10
19
0
10
37
0
0
10
0
0
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
10
10
0
10
0
0
10
0
10
0
0
0
0
% D
% Glu:
37
28
0
0
10
0
0
0
0
10
0
37
0
0
0
% E
% Phe:
0
0
0
0
19
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
19
37
0
0
0
19
0
10
0
0
0
10
0
10
% G
% His:
0
0
0
10
0
0
10
0
10
0
0
0
0
10
0
% H
% Ile:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
10
0
10
10
19
0
0
0
% K
% Leu:
10
19
10
10
0
37
0
10
10
0
37
10
0
0
0
% L
% Met:
0
0
0
0
0
10
10
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
0
0
10
46
28
% N
% Pro:
10
10
0
10
37
19
10
0
0
10
19
10
10
19
0
% P
% Gln:
0
0
0
0
0
0
0
0
37
0
0
0
19
0
0
% Q
% Arg:
19
10
0
0
28
19
10
37
0
10
19
0
0
19
19
% R
% Ser:
10
0
10
37
10
0
10
37
10
10
0
10
37
10
37
% S
% Thr:
0
0
10
19
0
0
19
0
10
0
0
10
0
0
10
% T
% Val:
19
0
10
0
0
0
0
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
0
0
10
10
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _